Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50001007
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267570(CHEMBL4081242)
Affinity DataIC50: 13nMAssay Description:Inhibition of human N-terminal His-tagged 11beta-HSD1 expressed in Escherichia coli using cortisol as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267595(CHEMBL4071679)
Affinity DataIC50: 101nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267560(CHEMBL4102864)
Affinity DataIC50: 213nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267600(CHEMBL4088895)
Affinity DataIC50: 244nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267592(CHEMBL4060927)
Affinity DataIC50: 400nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267561(CHEMBL4084451)
Affinity DataIC50: 454nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267570(CHEMBL4081242)
Affinity DataIC50: 460nMAssay Description:Inhibition of mouse N-terminal His-tagged 11beta-HSD1 expressed in Escherichia coli using cortisol as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267558(CHEMBL4065535)
Affinity DataIC50: 476nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267601(CHEMBL4087459)
Affinity DataIC50: 488nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267559(CHEMBL4102413)
Affinity DataIC50: 592nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267593(CHEMBL4059599)
Affinity DataIC50: 601nMAssay Description:Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267624(CHEMBL4064979)
Affinity DataIC50: 729nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267560(CHEMBL4102864)
Affinity DataIC50: 994nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267594(CHEMBL4103361)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267624(CHEMBL4064979)
Affinity DataIC50: 6.26E+3nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267594(CHEMBL4103361)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267560(CHEMBL4102864)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267561(CHEMBL4084451)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267560(CHEMBL4102864)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267558(CHEMBL4065535)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267593(CHEMBL4059599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50267559(CHEMBL4102413)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full-length mouse 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 1 hr by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed