Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50000061
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50: 52nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 108nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50: 189nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239860(CHEMBL4081343)
Affinity DataIC50: 447nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Heinrich-Heine-Universit£T D£Sseldorf

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed