Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50049310
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287008(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286381(8-(2-((1-acryloylpiperidin-3-yl)oxy)ethyl)-6-(2,6-...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238813(CHEMBL4083740)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238811(CHEMBL4073347)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238823(CHEMBL4086567)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287067(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238809(CHEMBL4084708)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287008(8-(2-((1-acryloylazetidin-3-yl)oxy)ethyl)-6-(2,6-d...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238806(CHEMBL4083151)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238804(CHEMBL4099578)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238805(CHEMBL4061286)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataKi:  1.30nMAssay Description:Irreversible inhibition of human FGFR2 preincubated with enzyme followed by peptide substrate addition by caliper capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287067(8-(2-((1-acryloylazetidin-3-yl)(methyl)amino)ethyl...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human FGFR2 preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238805(CHEMBL4061286)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238818(CHEMBL4064081)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238818(CHEMBL4064081)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238824(CHEMBL4064756)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataKi:  1.60nMAssay Description:Irreversible inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated with enzyme followed by peptide substrate addition by ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238803(CHEMBL4066763)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238803(CHEMBL4066763)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286523(8-(2-((1-acryloylpyrrolidin-3-yl)oxy)ethyl)-6-(2,6...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238821(CHEMBL4088057)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238816(CHEMBL4084079)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238821(CHEMBL4088057)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataKi:  2.20nMAssay Description:Irreversible inhibition of human FGFR3 preincubated with enzyme followed by peptide substrate addition by caliper capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286388(8-(2-(4-acryloylpiperazin-1-yl)ethyl)-6-(2,6-dichl...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286388(8-(2-(4-acryloylpiperazin-1-yl)ethyl)-6-(2,6-dichl...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238810(CHEMBL4092456)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238810(CHEMBL4092456)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238802(CHEMBL4095783)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238804(CHEMBL4099578)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238812(CHEMBL4100201)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287559(8-(2-((1-acryloylpiperidin-4-yl)(methyl)amino)ethy...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM287559(8-(2-((1-acryloylpiperidin-4-yl)(methyl)amino)ethy...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human FGFR3 preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238820(CHEMBL4072676)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human FGFR1 using 5-FAM-KKKKEEIYFFF-NH2 as substrate preincubated for 15 mins followed by peptide substrate addition measured after 3 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238814(CHEMBL4085605)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286381(8-(2-((1-acryloylpiperidin-3-yl)oxy)ethyl)-6-(2,6-...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238802(CHEMBL4095783)
Affinity DataIC50: 6nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286523(8-(2-((1-acryloylpyrrolidin-3-yl)oxy)ethyl)-6-(2,6...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM286984(8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human CSF1R preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238815(CHEMBL4068712)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238808(CHEMBL4102642)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238808(CHEMBL4102642)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238806(CHEMBL4083151)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238809(CHEMBL4084708)
Affinity DataIC50: 11nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238824(CHEMBL4064756)
Affinity DataIC50: 12nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
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