Compile Data Set for Download or QSAR
Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50000822
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261255BDBM50261255(CHEMBL4084436)
Affinity DataKi:  0.300nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261268BDBM50261268(CHEMBL4062758)
Affinity DataKi:  0.400nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 120128BDBM120128(US8697708, 2)
Affinity DataKi:  0.5nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261261BDBM50261261(CHEMBL4075453)
Affinity DataKi:  0.5nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261256BDBM50261256(CHEMBL4071399)
Affinity DataKi:  0.5nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261254BDBM50261254(CHEMBL4074130)
Affinity DataKi:  0.600nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261274BDBM50261274(CHEMBL4062680)
Affinity DataKi:  0.600nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261260BDBM50261260(CHEMBL4069942)
Affinity DataKi:  0.600nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261270BDBM50261270(CHEMBL4093872)
Affinity DataKi:  0.600nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261276BDBM50261276(CHEMBL4092116)
Affinity DataKi:  0.600nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261269BDBM50261269(CHEMBL4092191)
Affinity DataKi:  0.700nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261273BDBM50261273(CHEMBL4076947)
Affinity DataKi:  0.700nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261257BDBM50261257(CHEMBL4099854)
Affinity DataKi:  0.700nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261283BDBM50261283(CHEMBL4093172)
Affinity DataKi:  0.800nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261262BDBM50261262(CHEMBL4070262)
Affinity DataKi:  1nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261267BDBM50261267(CHEMBL4097446)
Affinity DataKi:  1.20nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261271BDBM50261271(CHEMBL4080904)
Affinity DataKi:  1.20nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261253BDBM50261253(CHEMBL4100889)
Affinity DataKi:  1.30nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261215BDBM50261215(CHEMBL2387223)
Affinity DataKi:  1.60nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261218BDBM50261218(CHEMBL4064189)
Affinity DataKi:  1.70nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261284BDBM50261284(CHEMBL4065419)
Affinity DataKi:  3.20nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434821BDBM50434821(CHEMBL2387224)
Affinity DataKi:  4.80nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261272BDBM50261272(CHEMBL4105148)
Affinity DataKi:  5.10nMAssay Description:Inhibition of TYK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261262BDBM50261262(CHEMBL4070262)
Affinity DataKi:  5.40nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261270BDBM50261270(CHEMBL4093872)
Affinity DataKi:  6.5nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261283BDBM50261283(CHEMBL4093172)
Affinity DataKi:  6.60nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261282BDBM50261282(CHEMBL4068427)
Affinity DataKi:  8.80nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261275BDBM50261275(CHEMBL4093092)
Affinity DataKi:  9.90nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261271BDBM50261271(CHEMBL4080904)
Affinity DataKi:  10nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261219BDBM50261219(CHEMBL4075131)
Affinity DataKi:  13nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261255BDBM50261255(CHEMBL4084436)
Affinity DataKi:  14nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261267BDBM50261267(CHEMBL4097446)
Affinity DataKi:  14nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261261BDBM50261261(CHEMBL4075453)
Affinity DataKi:  16nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261216BDBM50261216(CHEMBL4082575)
Affinity DataKi:  16nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261217BDBM50261217(CHEMBL4101734)
Affinity DataKi:  17nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261220BDBM50261220(CHEMBL4089568)
Affinity DataKi:  19nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261221BDBM50261221(CHEMBL4085414)
Affinity DataKi:  20nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261268BDBM50261268(CHEMBL4062758)
Affinity DataKi:  21nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261273BDBM50261273(CHEMBL4076947)
Affinity DataKi:  22nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261276BDBM50261276(CHEMBL4092116)
Affinity DataKi:  23nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261273BDBM50261273(CHEMBL4076947)
Affinity DataKi:  24nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261256BDBM50261256(CHEMBL4071399)
Affinity DataKi:  26nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 120128BDBM120128(US8697708, 2)
Affinity DataKi:  26nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434821BDBM50434821(CHEMBL2387224)
Affinity DataKi:  28nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261222BDBM50261222(CHEMBL4103341)
Affinity DataKi:  31nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261260BDBM50261260(CHEMBL4069942)
Affinity DataKi:  34nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261269BDBM50261269(CHEMBL4092191)
Affinity DataEC50:  35nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261274BDBM50261274(CHEMBL4062680)
Affinity DataKi:  36nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261216BDBM50261216(CHEMBL4082575)
Affinity DataKi:  42nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261284BDBM50261284(CHEMBL4065419)
Affinity DataKi:  43nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2020
Entry Details Article
PubMed
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