Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50019114
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50525810(CHEMBL4451680)
Affinity DataEC50:  0.100nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataEC50:  0.200nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615419(CHEMBL5285270)
Affinity DataKi:  0.300nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615411(CHEMBL5283960)
Affinity DataEC50:  0.300nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615418(CHEMBL5270265)
Affinity DataEC50:  0.400nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615418(CHEMBL5270265)
Affinity DataKi:  0.5nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50525810(CHEMBL4451680)
Affinity DataKi:  0.600nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615420(CHEMBL5274183)
Affinity DataKi:  0.600nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615421(CHEMBL5288889)
Affinity DataKi:  0.600nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615421(CHEMBL5288889)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615419(CHEMBL5285270)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615420(CHEMBL5274183)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615412(CHEMBL5273254)
Affinity DataEC50:  0.700nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615409(CHEMBL5285176)
Affinity DataKi:  0.800nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615413(CHEMBL5267299)
Affinity DataEC50:  0.800nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615412(CHEMBL5273254)
Affinity DataKi:  0.800nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615423(CHEMBL5281542)
Affinity DataKi:  0.870nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615409(CHEMBL5285176)
Affinity DataEC50:  0.900nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615408(CHEMBL5278683)
Affinity DataEC50:  1nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataKi:  1.20nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615416(CHEMBL5286329)
Affinity DataEC50:  1.20nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615417(CHEMBL5281783)
Affinity DataEC50:  1.40nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615413(CHEMBL5267299)
Affinity DataKi:  1.40nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615425(CHEMBL5271387)
Affinity DataKi:  1.60nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615411(CHEMBL5283960)
Affinity DataKi:  1.90nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615421(CHEMBL5288889)
Affinity DataKi:  2.10nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615408(CHEMBL5278683)
Affinity DataKi:  2.20nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50525810(CHEMBL4451680)
Affinity DataKi:  2.40nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615417(CHEMBL5281783)
Affinity DataKi:  2.70nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615414(CHEMBL5277860)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615424(CHEMBL5277417)
Affinity DataKi:  3nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50247053(Tiprolisant | 1-(3-(3-(4-chlorophenyl)propoxy)prop...)
Affinity DataKi:  3nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615414(CHEMBL5277860)
Affinity DataKi:  3.10nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615420(CHEMBL5274183)
Affinity DataKi:  3.20nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615418(CHEMBL5270265)
Affinity DataKi:  3.60nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615414(CHEMBL5277860)
Affinity DataEC50:  3.90nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615416(CHEMBL5286329)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615415(CHEMBL5280351)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615422(CHEMBL5288750)
Affinity DataKi:  4.30nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615415(CHEMBL5280351)
Affinity DataEC50:  4.40nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615415(CHEMBL5280351)
Affinity DataKi:  5nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615416(CHEMBL5286329)
Affinity DataKi:  5.20nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615419(CHEMBL5285270)
Affinity DataKi:  5.60nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50525810(CHEMBL4451680)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615413(CHEMBL5267299)
Affinity DataKi:  6.10nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615414(CHEMBL5277860)
Affinity DataKi:  7nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615423(CHEMBL5281542)
Affinity DataKi:  7.30nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615417(CHEMBL5281783)
Affinity DataKi:  7.5nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615412(CHEMBL5273254)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHistamine H3 receptor(Rat)
Chemical Works of Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50615408(CHEMBL5278683)
Affinity DataKi:  7.60nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
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