Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 50000878
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.17E+3nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.46E+3nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 2.66E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.34E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.35E+3nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.75E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 4.01E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.83E+3nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 6.43E+3nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.62E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.32E+4nMAssay Description:Competitive inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by Lineweaver-Burk double re...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.57E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Human)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetCholinesterase(Horse)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by L...More data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetLiver carboxylesterase(Pig)
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Institute of Physiologically Active Compounds Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of pig liver carboxylesterase using 4-nitrophenol acetate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair

3D Structure (crystal)





















