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Found 32 Enz. Inhib. hit(s) with all data for entry = 50000445
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.0480nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250449(CHEMBL4065490)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50142700(CHEMBL326684)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250451(CHEMBL4088589)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250448(CHEMBL607351)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250448(CHEMBL607351)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250448(CHEMBL607351)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250452(CHEMBL4074110)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  1.80nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250449(CHEMBL4065490)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250451(CHEMBL4088589)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250449(CHEMBL4065490)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250451(CHEMBL4088589)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50142700(CHEMBL326684)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50142700(CHEMBL326684)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250452(CHEMBL4074110)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250452(CHEMBL4074110)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250448(CHEMBL607351)
Affinity DataEC50:  0.320nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250452(CHEMBL4074110)
Affinity DataEC50:  9nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250451(CHEMBL4088589)
Affinity DataEC50:  3nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250450(CHEMBL4103328)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50250449(CHEMBL4065490)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50142700(CHEMBL326684)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed