Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50001994
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataKi:  17nMAssay Description:Uncompetitive inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldeh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 20nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 21nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50: 58nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50: 58nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataKi:  66nMAssay Description:Uncompetitive inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50: 141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50: 141nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451730(CHEMBL4207775)
Affinity DataIC50: 169nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 227nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451733(CHEMBL1897400)
Affinity DataIC50: 340nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451734(CHEMBL4219003)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451731(CHEMBL4216153)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50: 9.43E+3nMAssay Description:Inhibition of recombinant human AKR1B10More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451729(CHEMBL4206601)
Affinity DataIC50: 9.98E+3nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451730(CHEMBL4207775)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451733(CHEMBL1897400)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of ALR2 in Wistar rat eye lens assessed as reduction in NADPH consumption preincubated for 1 min followed by D,L-glyceraldehyde addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451735(CHEMBL4207499)
Affinity DataIC50: 4.38E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 5.61E+4nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50451732(CHEMBL4202616)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ALR1 in Wistar rat kidney assessed as reduction in NADPH consumption preincubated for 1 min followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed