Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50002138
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 200nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human MNC suspension after 20 hrs by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454030BDBM50454030(CHEMBL4214663)
Affinity DataIC50: 300nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453983BDBM50453983(CHEMBL4215614)
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454032BDBM50454032(CHEMBL4209925)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453998BDBM50453998(CHEMBL4206211)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453997BDBM50453997(CHEMBL4204861)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454026BDBM50454026(CHEMBL4216705)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453995BDBM50453995(CHEMBL4212779)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454033BDBM50454033(CHEMBL4211218)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453993BDBM50453993(CHEMBL4206607)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453988BDBM50453988(CHEMBL4202770)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454006BDBM50454006(CHEMBL4213788)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453991BDBM50453991(CHEMBL4211883)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453990BDBM50453990(CHEMBL4209097)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454000BDBM50454000(CHEMBL4204753)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453992BDBM50453992(CHEMBL4216524)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454028BDBM50454028(CHEMBL4216431)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454004BDBM50454004(CHEMBL4213498)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454008BDBM50454008(CHEMBL4217242)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Mouse)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454023BDBM50454023(CHEMBL4215786)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of mouse recombinant TNF-alpha binding to antibody preincubated for 30 mins followed by antibody addition measured after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453986BDBM50453986(CHEMBL4212953)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454005BDBM50454005(CHEMBL4208563)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453994BDBM50453994(CHEMBL4211594)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454025BDBM50454025(CHEMBL4208862)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373071BDBM50373071(CHEMBL255489)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TNF-alpha (unknown origin) binding to TNFR1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453987BDBM50453987(CHEMBL4203548)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453989BDBM50453989(CHEMBL4204234)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454022BDBM50454022(CHEMBL4206575)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453985BDBM50453985(CHEMBL4208400)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454007BDBM50454007(CHEMBL4212270)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454021BDBM50454021(CHEMBL4217876)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454020BDBM50454020(CHEMBL4207908)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454009BDBM50454009(CHEMBL4218009)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453999BDBM50453999(CHEMBL4204426)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454003BDBM50454003(CHEMBL4204400)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454002BDBM50454002(CHEMBL4204718)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454001BDBM50454001(CHEMBL4205907)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454031BDBM50454031(CHEMBL4215621)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454029BDBM50454029(CHEMBL4214427)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453996BDBM50453996(CHEMBL4204585)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454024BDBM50454024(CHEMBL4217894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453984BDBM50453984(CHEMBL4212933)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453982BDBM50453982(CHEMBL4207994)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454027BDBM50454027(CHEMBL4212813)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed