Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50002653
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 130nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461196BDBM50461196(CHEMBL4228405)
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461206BDBM50461206(CHEMBL4225898)
Affinity DataIC50: 460nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461204BDBM50461204(CHEMBL4227576)
Affinity DataIC50: 750nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461197BDBM50461197(CHEMBL4226687)
Affinity DataIC50: 810nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461198BDBM50461198(CHEMBL4225848)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461205BDBM50461205(CHEMBL4225048)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461194BDBM50461194(CHEMBL4228935)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461200BDBM50461200(CHEMBL4225322)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461192BDBM50461192(CHEMBL4225380)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461191BDBM50461191(CHEMBL4228262)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461195BDBM50461195(CHEMBL4227837)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461207BDBM50461207(CHEMBL4227439)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461209BDBM50461209(CHEMBL4225407)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461208BDBM50461208(CHEMBL4228094)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461203BDBM50461203(CHEMBL4228205)
Affinity DataIC50: 5.22E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461190BDBM50461190(CHEMBL4226417)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461199BDBM50461199(CHEMBL4226162)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461201BDBM50461201(CHEMBL4228325)
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461202BDBM50461202(CHEMBL4228289)
Affinity DataIC50: 6.57E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461193BDBM50461193(CHEMBL4228664)
Affinity DataIC50: 8.71E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed