Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50003054
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466323(CHEMBL4279353)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466316(CHEMBL4276669)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466325(CHEMBL4279430)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466328(CHEMBL4290540)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466206(CHEMBL4281335)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466320(CHEMBL4277754)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466322(CHEMBL4292583)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466316(CHEMBL4276669)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50463727(CHEMBL4245727)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466321(CHEMBL4285813)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466331(CHEMBL4277875)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466325(CHEMBL4279430)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466323(CHEMBL4279353)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466206(CHEMBL4281335)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466331(CHEMBL4277875)
Affinity DataIC50:  7nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466315(CHEMBL4291033)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466319(CHEMBL4280401)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466321(CHEMBL4285813)
Affinity DataIC50:  14nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)
Affinity DataIC50:  14nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466330(CHEMBL4293010)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466324(CHEMBL4286664)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466322(CHEMBL4292583)
Affinity DataIC50:  41nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466320(CHEMBL4277754)
Affinity DataIC50:  44nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466206(CHEMBL4281335)
Affinity DataIC50:  52nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466318(CHEMBL4287216)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466326(CHEMBL4282745)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466327(CHEMBL4289625)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466329(CHEMBL4290625)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50466317(CHEMBL4279288)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair