Found 13 Enz. Inhib. hit(s) with all data for entry = 50007310 Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as reduction in phenacetin-O-deethylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of CYP3A in human liver microsomes assessed as reduction in midazolam 1'-hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as reduction in omeprazole hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as reduction in dextromethorphan O-demethylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of UGT1A1 in human liver microsomes assessed as reduction in SN-38 glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A4(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of UGT1A4 in human liver microsomes assessed as reduction in trifluoperazine N-glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 2B7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of UGT2B7 in human liver microsomes assessed as reduction in naloxone 3-glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of UGT1A9 in human liver microsomes assessed as reduction in mycophenolic acid glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
