BindingDB PrimarySearch

Found 47 Enz. Inhib. hit(s) with all data for entry = 50004987

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537558(Narlaprevir | SCH 900518 | SCH-900518)

Ki: 6nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase MCE
PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537563(CHEMBL4634405)

Ki: 20nMAssay Description:Inhibition of Epidermal growth factor receptor from human A431 cell membranesMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

KEGG PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50103860(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)

Ki: 27nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537564(CHEMBL4644516)

Ki: 40nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

KEGG PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537569(CHEMBL4646328)

Ki: 600nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50103860(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)

Ki: 1.00E+3nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)

IC50: 0.200nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)

IC50: 2nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase MCE
PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537589(CHEMBL4287268)

IC50: 3nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537581(CHEMBL4638107)

IC50: 4nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537583(CHEMBL4638630)

IC50: 4.30nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537585(CHEMBL4646449)

IC50: 5nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537579(CHEMBL4635161)

IC50: 6nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537587(CHEMBL4633142)

IC50: 6nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537578(CHEMBL245328)

IC50: 7.20nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50379197(CHEMBL2011266)

IC50: 8nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

CHEMBL MMDB PC cid PC sid PDB

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537574(CHEMBL4643906)

IC50: 10nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537575(CHEMBL4638877)

IC50: 10nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537588(CHEMBL4643189)

IC50: 17nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50142061((2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imi...)

IC50: 19nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50081635(CHEMBL3422107)

IC50: 19nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537580(CHEMBL480816)

IC50: 27nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537566(CHEMBL4640558)

IC50: 33nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

KEGG PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537586(CHEMBL4641917)

IC50: 39nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase P236LMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537571(CHEMBL390883)

IC50: 42nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537565(CHEMBL4649647)

IC50: 51nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

KEGG PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537584(CHEMBL4636786)

IC50: 53nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50187149(6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-ph...)

IC50: 58nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase V106AMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537582(CHEMBL1783101)

IC50: 70nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50137504(1-Cyclohexyl-2-furan-2-yl-1H-benzoimidazole-5-carb...)

IC50: 160nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537572(CHEMBL1087567)

IC50: 300nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50370763(CHEMBL1203926)

IC50: 340nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537576(CHEMBL4633554)

IC50: 340nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50160199(6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol | CHEMBL18...)

IC50: 500nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537573(CHEMBL4642429)

IC50: 550nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537577(CHEMBL4639473)

IC50: 600nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase V106AMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537567(CHEMBL4632418)

IC50: 800nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)

IC50: 1.60E+3nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase V106AMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537559(CHEMBL4640738)

IC50: 3.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Nonstructural protein 5A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50181949(2-(4-(benzyloxy)phenyl)-1-cyclopentyl-1H-benzo[d]i...)

IC50: 3.20E+3nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537591(CHEMBL3617579)

IC50: 8.80E+3nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase G190AMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

Genome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537568(CHEMBL4641913)

IC50: 1.50E+4nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair

PDB
UniProtKB/TrEMBL
GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537590(CHEMBL4641216)

IC50: 1.57E+4nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase V106AMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537570(CHEMBL474496)

IC50: 4.50E+4nMAssay Description:Inhibitory activity against HIV-1 wild-type reverse transcriptase.More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537561(CHEMBL388502)

Kd: 1.70E+3nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid PDB

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537560(CHEMBL427101)

Kd: >1.00E+5nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase PC cid PC sid

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Institute Of Pharmaceutical Education And Research

Curated by ChEMBL

BDBM50537562(CHEMBL223720)

Kd: 720nMAssay Description:Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

PC cid PC sid

Details Article PubMed