Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 50009571
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  21nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  21nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  24nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  24nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  30nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  30nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  34nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  34nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  38nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  38nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  43nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  43nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  44nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  44nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  46nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  46nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  55nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  55nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  58nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  58nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  61nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  61nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  64nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)
Affinity DataEC50:  64nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  120nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  120nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  160nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  160nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  170nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530020(CHEMBL4469773)
Affinity DataEC50:  170nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  180nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50530019(CHEMBL4455349)
Affinity DataEC50:  180nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Emory University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50333129(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1...)
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
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