Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50002426
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7962BDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 3nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022222BDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022224BDBM50022224(2-Imidazol-1-ylmethyl-benzofuran-5-carboxylic acid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022217BDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022216BDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 17nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022219BDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50: 18nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022220BDBM50022220(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-5...)
Affinity DataIC50: 22nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022226BDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50: 25nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022230BDBM50022230(3-Bromo-2-imidazol-1-ylmethyl-benzo[b]thiophene-5-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022215BDBM50022215(3-Bromo-2-imidazol-1-ylmethyl-benzofuran-5-carboxy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022223BDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: 31nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022221BDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 32nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022229BDBM50022229(6-Imidazol-1-ylmethyl-naphthalene-2-carboxylic aci...)
Affinity DataIC50: 34nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022222BDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: 34nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022218BDBM50022218(2-Imidazol-1-ylmethyl-3-methyl-1H-indole-5-carboxy...)
Affinity DataIC50: 37nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022227BDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50: 40nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022228BDBM50022228(2-Imidazol-1-ylmethyl-3-methylsulfanyl-benzo[b]thi...)
Affinity DataIC50: 43nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022225BDBM50022225(6-Imidazol-1-ylmethyl-naphthalene-1-carboxylic aci...)
Affinity DataIC50: 71nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 7962BDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022222BDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022223BDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7962BDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022216BDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7962BDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022216BDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022217BDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022217BDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022227BDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022230BDBM50022230(3-Bromo-2-imidazol-1-ylmethyl-benzo[b]thiophene-5-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022223BDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022219BDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50022226BDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022221BDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022223BDBM50022223(3-Chloro-2-imidazol-1-ylmethyl-benzofuran-5-carbox...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022220BDBM50022220(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-5...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022222BDBM50022222(2-Imidazol-1-ylmethyl-3-methyl-benzofuran-5-carbox...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022227BDBM50022227(3-Chloro-2-imidazol-1-ylmethyl-benzo[b]thiophene-6...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022216BDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022226BDBM50022226(6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022217BDBM50022217(2-Imidazol-1-ylmethyl-benzo[b]thiophene-5-carboxyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022219BDBM50022219(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-6...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed