Found 4 Enz. Inhib. hit(s) with all data for entry = 50010132 TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 2.10E+4nMAssay Description:Inhibition of mouse HCN1 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.94E+4nMAssay Description:Inhibition of mouse HCN2 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Mus musculus)
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Inhibition of HCN4 in C57BL/6J mouse thalamocortical relay neuron assessed as reduction in hyperpolarization current at holding potential of -120 mV ...More data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
University Of Florence
Curated by ChEMBL
University Of Florence
Curated by ChEMBL
Affinity DataEC50: 3.98E+3nMAssay Description:Inhibition of human HCN4 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
