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Found 28 Enz. Inhib. hit(s) with all data for entry = 50007759
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512383(CHEMBL137766)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50147349((R)-3-(S)-Amino-2-hydroxy-5-phenyl-pentanoic acid ...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50147344((2S,3R)-3-Amino-4-cyclohexyl-2-hydroxy-N-{4-[3-(3,...)
Affinity DataIC50:  177nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50147357((R)-3-(S)-Amino-2-hydroxy-4-phenyl-N-{4-[3-((E)-3,...)
Affinity DataIC50:  755nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  4.40E+3nMAssay Description:Competitive inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512380(CHEMBL4565675)
Affinity DataIC50:  6.40E+3nMAssay Description:Competitive inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.80E+3nMAssay Description:Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  8.80E+3nMAssay Description:Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512385(CHEMBL4521296)
Affinity DataIC50:  9.10E+3nMAssay Description:Competitive inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512384(CHEMBL1910917 | Phenyl-3'',4'',5''-Trimethoxycinna...)
Affinity DataIC50:  9.40E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232202((E)-N-Octyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232204(3,4,5-Trimethoxycinnamic acid (TMCA))
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512381(CHEMBL4521063)
Affinity DataIC50:  1.80E+4nMAssay Description:Competitive inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM50512382(CHEMBL4444323)
Affinity DataIC50:  2.72E+4nMAssay Description:Competitive inhibition of soluble epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed