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Found 21 Enz. Inhib. hit(s) with all data for entry = 50009011
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50335390(CHEMBL1651630 | N-Hexoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524479(CHEMBL4459011)
Affinity DataIC50:  1nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524480(CHEMBL4559665)
Affinity DataIC50:  4nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50335387(CHEMBL1651633 | N-Nonoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  34nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50156357(2-Hydroxymethyl-1-nonyl-piperidine-3,4,5-triol | C...)
Affinity DataIC50:  35nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524486(CHEMBL4577406)
Affinity DataIC50:  44nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524485(CHEMBL4435506)
Affinity DataIC50:  65nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524481(CHEMBL4459494)
Affinity DataIC50:  137nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524484(CHEMBL187262)
Affinity DataIC50:  260nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524482(CHEMBL4460711)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50335390(CHEMBL1651630 | N-Hexoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524483(CHEMBL4435540)
Affinity DataIC50:  3.67E+4nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50243651(CHEMBL4061367)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  1.18E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524482(CHEMBL4460711)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50524483(CHEMBL4435540)
Affinity DataIC50:  6.03E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed