Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50007385
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038879BDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038879BDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508983BDBM50508983(CHEMBL4464623)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508977BDBM50508977(CHEMBL4451993)
Affinity DataKi:  3.5nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508977BDBM50508977(CHEMBL4451993)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038879BDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of first step of the binding event pre-incubated for 2 hrs before addition of ZGP-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508977BDBM50508977(CHEMBL4451993)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of first step of the binding event pre-incubated for 2 hrs before addition of ZGP-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326390BDBM50326390((2S,4S)-1-({(2S,4S)-4-[2-(1,3-Dihydro-2H-isoindol-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050513BDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508979BDBM50508979(CHEMBL4558566)
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant human POP pre-incubated for 2 hrs before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393843BDBM50393843(CHEMBL2159748)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393843BDBM50393843(CHEMBL2159748)
Affinity DataKi:  25nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508979BDBM50508979(CHEMBL4558566)
Affinity DataKi:  29nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of second step of inhibition pre-incubated for 2 hrs before addition of ZGP-pNA sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431242BDBM50431242(CHEMBL2333026)
Affinity DataIC50: 36nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508979BDBM50508979(CHEMBL4558566)
Affinity DataKi:  60nMAssay Description:Inhibition of recombinant human POP assessed as affinity constant of first step of the binding event pre-incubated for 2 hrs before addition of ZGP-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050513BDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 66nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508979BDBM50508979(CHEMBL4558566)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393842BDBM50393842(CHEMBL2159749)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508978BDBM50508978(CHEMBL4462021)
Affinity DataKi:  170nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508981BDBM50508981(CHEMBL4437462)
Affinity DataKi:  290nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508980BDBM50508980(CHEMBL4584206)
Affinity DataKi:  620nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050513BDBM50050513(Ketopyrrolidine derivative | (R)-1-((S)-2-amino-3-...)
Affinity DataIC50: 980nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508982BDBM50508982(CHEMBL4474579)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431242BDBM50431242(CHEMBL2333026)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508983BDBM50508983(CHEMBL4464623)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508984BDBM50508984(CHEMBL4453293)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant human POP pre-incubated for 30 mins before addition of ZGP-pNA substrate by absorbance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed