Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010469
TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466808BDBM50466808(AZD-1152-HQPA | Barasertib)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of Aurora A (unknown origin) after 1 hr in presence of ATP by Kinase-Glo reagent-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of N-terminal His6-tagged Aurora C (1 to 309 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B (unknown origin) after 1 hr in presence of ATP by Kinase-Glo reagent-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  18nMAssay Description:Inhibition of N-terminal His6-tagged Aurora B (1 to 403 residues) (unknown origin) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539202BDBM50539202(CHEMBL4646386)
Affinity DataIC50: 293nMAssay Description:Inhibition of Aurora B (unknown origin) after 1 hr in presence of ATP by Kinase-Glo reagent-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539202BDBM50539202(CHEMBL4646386)
Affinity DataIC50: 309nMAssay Description:Inhibition of Aurora A (unknown origin) after 1 hr in presence of ATP by Kinase-Glo reagent-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539201BDBM50539201(CHEMBL4643443)
Affinity DataIC50: 329nMAssay Description:Inhibition of Aurora B (unknown origin) after 1 hr in presence of ATP by Kinase-Glo reagent-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170831BDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora C expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170831BDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora A expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Lanzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170831BDBM50170831(N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed