Found 42 Enz. Inhib. hit(s) with all data for entry = 50010490 
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Biogen
Curated by ChEMBL
Biogen
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.87E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMAssay Description:Activation of Nrf2 in human spinal cord astrocytes assessed as increase in glutathione level after 20 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.61E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 360nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.27E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.24E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 8.84E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 690nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 14nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataKd: 56nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.50E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.29E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.82E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0700nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.880nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.39E+3nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
