Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50010395
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538416BDBM50538416(CHEMBL4644835 | US11236045, Example 25)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538393BDBM50538393(CHEMBL4647321 | US11236045, Example 1)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155926BDBM50155926(CHEMBL3183703)
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538418BDBM50538418(CHEMBL4641961 | US11236045, Example 54)
Affinity DataIC50: 12nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538405BDBM50538405(CHEMBL4642066)
Affinity DataIC50: 15nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538407BDBM50538407(CHEMBL4647621 | US11236045, Example 22)
Affinity DataIC50: 21nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538421BDBM50538421(CHEMBL4649141 | US11236045, Example 30)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538417BDBM50538417(CHEMBL4643205 | US11236045, Example 55)
Affinity DataIC50: 34nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538406BDBM50538406(CHEMBL4640151)
Affinity DataIC50: 35nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538420BDBM50538420(CHEMBL4636825 | US11236045, Example 56)
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538419BDBM50538419(CHEMBL4646271)
Affinity DataIC50: 110nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538415BDBM50538415(CHEMBL4635816)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538414BDBM50538414(CHEMBL4644503)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538413BDBM50538413(CHEMBL4637610)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538412BDBM50538412(CHEMBL4643062)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538411BDBM50538411(CHEMBL4646037)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538410BDBM50538410(CHEMBL4649429)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538409BDBM50538409(CHEMBL4644865)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538408BDBM50538408(CHEMBL4634682)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538404BDBM50538404(CHEMBL4636808)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538403BDBM50538403(CHEMBL4649881)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538402BDBM50538402(CHEMBL4641660)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538401BDBM50538401(CHEMBL4649621)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538400BDBM50538400(CHEMBL4643208)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538399BDBM50538399(CHEMBL4643011)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538398BDBM50538398(CHEMBL4640804)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538397BDBM50538397(CHEMBL4633769)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538396BDBM50538396(CHEMBL4633580)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538395BDBM50538395(CHEMBL4634472)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538394BDBM50538394(CHEMBL4640644)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538421BDBM50538421(CHEMBL4649141 | US11236045, Example 30)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538420BDBM50538420(CHEMBL4636825 | US11236045, Example 56)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538419BDBM50538419(CHEMBL4646271)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538418BDBM50538418(CHEMBL4641961 | US11236045, Example 54)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538417BDBM50538417(CHEMBL4643205 | US11236045, Example 55)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538416BDBM50538416(CHEMBL4644835 | US11236045, Example 25)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538407BDBM50538407(CHEMBL4647621 | US11236045, Example 22)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538393BDBM50538393(CHEMBL4647321 | US11236045, Example 1)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed