Compile Data Set for Download or QSAR
Report error Found 138 Enz. Inhib. hit(s) with all data for entry = 50007697
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.173nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.255nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 0.534nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 90 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511839(CHEMBL4534191)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 90 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(acetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511828(CHEMBL4555545)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511839(CHEMBL4534191)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511827(CHEMBL4580907)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511847(CHEMBL4531072)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511829(CHEMBL4515793)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511845(CHEMBL4435691)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511847(CHEMBL4531072)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511828(CHEMBL4555545)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511843(CHEMBL4474900)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511826(CHEMBL4465293)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511825(CHEMBL4444219)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511845(CHEMBL4435691)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511843(CHEMBL4474900)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511839(CHEMBL4534191)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511840(CHEMBL4558922)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511831(CHEMBL4583564)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Displayed 1 to 50 (of 138 total ) | Next | Last >>
Jump to: