Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010533
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539783(CHEMBL4637788)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539782(CHEMBL4648427)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539782(CHEMBL4648427)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539783(CHEMBL4637788)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50291290(CHEMBL4173326)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50291290(CHEMBL4173326)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539784(CHEMBL1096940)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 4.36E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539784(CHEMBL1096940)
Affinity DataIC50: 6.48E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50179013(moracin O | CHEMBL205924)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed