Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50010786
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542080(CHEMBL4649390)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542079(CHEMBL4647102)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM232964(US9353113, Ref. Ex. 2)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542078(CHEMBL4634704)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542077(CHEMBL4634102)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542077(CHEMBL4634102)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542080(CHEMBL4649390)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542078(CHEMBL4634704)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542079(CHEMBL4647102)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM232964(US9353113, Ref. Ex. 2)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542075(CHEMBL4634540)
Affinity DataIC50: 16nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542074(CHEMBL4642470)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542070(CHEMBL4634784)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542075(CHEMBL4634540)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542076(CHEMBL4643803)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542069(CHEMBL4649090)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542076(CHEMBL4643803)
Affinity DataIC50: 25nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542072(CHEMBL4645794)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542073(CHEMBL4639112)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM325558(6-[9-(3-fluorobenzyl)-5,6,8,9-tetrahydro-7H-pyrido...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542071(CHEMBL4643425)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542067(CHEMBL4641471)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542068(CHEMBL4648748)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542070(CHEMBL4634784)
Affinity DataIC50: 260nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542066(CHEMBL4638236)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAutotaxin(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542065(CHEMBL4634304)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed