Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50012757
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559974BDBM50559974(CHEMBL4790850)
Affinity DataEC50:  10nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559973BDBM50559973(CHEMBL4790858)
Affinity DataEC50:  40nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559975BDBM50559975(CHEMBL4753374)
Affinity DataEC50:  220nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559983BDBM50559983(CHEMBL4800568)
Affinity DataEC50:  230nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559976BDBM50559976(CHEMBL4785159)
Affinity DataEC50:  250nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559977BDBM50559977(CHEMBL4777918)
Affinity DataEC50:  280nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559978BDBM50559978(CHEMBL4745690)
Affinity DataEC50:  330nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559984BDBM50559984(CHEMBL4788014)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559985BDBM50559985(CHEMBL4799568)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559986BDBM50559986(CHEMBL4749840)
Affinity DataEC50:  630nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559979BDBM50559979(CHEMBL4798704)
Affinity DataEC50:  700nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559980BDBM50559980(CHEMBL4763502)
Affinity DataEC50:  830nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559963BDBM50559963(CHEMBL4788965)
Affinity DataIC50: 900nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559964BDBM50559964(CHEMBL4757017)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036632BDBM50036632(CHEMBL3354284)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036610BDBM50036610(CHEMBL3354264)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036612BDBM50036612(CHEMBL3354266)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559965BDBM50559965(CHEMBL4790126)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036611BDBM50036611(CHEMBL3354265)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559981BDBM50559981(CHEMBL4791250)
Affinity DataEC50:  5.05E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036629BDBM50036629(CHEBI:66876 | Avanafil | Stendra | TA-1790)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036629BDBM50036629(CHEBI:66876 | Avanafil | Stendra | TA-1790)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036616BDBM50036616(CHEMBL3354270)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559966BDBM50559966(CHEMBL4749671)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559967BDBM50559967(CHEMBL4741817)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036631BDBM50036631(CHEMBL3352836)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559982BDBM50559982(CHEMBL4747542)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559968BDBM50559968(CHEMBL4790060)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036618BDBM50036618(CHEMBL3354272)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036617BDBM50036617(CHEMBL3354271)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036615BDBM50036615(CHEMBL3354269)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036620BDBM50036620(CHEMBL3354274)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559971BDBM50559971(CHEMBL4747008)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559969BDBM50559969(CHEMBL4781808)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036622BDBM50036622(CHEMBL3354276)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559970BDBM50559970(CHEMBL4798650)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Cairo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559972BDBM50559972(CHEMBL4748431)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed