Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50012973
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 69nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 78nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 93nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 93nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 110nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate preincubated in presence of NAD+ followed by substrate addition by HPLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 120nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SIRT2 deacetylation activity using H3K9Ac as substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate preincubated in presence of NAD+ followed by substrate addition by HPLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 370nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate preincubated in presence of NAD+ followed by substrate addition by HPLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human SIRT1 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human SIRT1 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT1 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT2 defatty-acylation activity using peptide substrate in presence of NAD+ by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT3 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT3 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT3 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT5 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT5 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT5 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561912(CHEMBL4798823)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT6 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50561913(CHEMBL4762508)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT6 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50276140(CHEMBL4129995)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human SIRT6 deacetylation activity using H3K9Ac as substrate preincubated for 15 mins in presence of NAD+ followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed