Found 32 Enz. Inhib. hit(s) with all data for entry = 50013552 TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 180nMAssay Description:Inhibition of human HDAC8 using using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of human HDAC8 using using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate by fluorescence methodMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human HDAC6 using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 20 mins by...More data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 50 mins by thio-glo reagent based fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human HDAC6 using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human HDAC6 using Z(Tfa)Lys-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by tryps...More data for this Ligand-Target Pair
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of human HDAC6 using Z-Lys(Ac)-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of human HDAC6 using Z-Lys(Ac)-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of human HDAC8 using using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by tryps...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human HDAC6 using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition and measured after 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using ZMAL(Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by tryps...More data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of Schistosoma mansoni ATPDase1 preincubated for 30 mins followed by addition of ATP/ADP by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of Schistosoma mansoni ATPDase1 incubated for 30 minsMore data for this Ligand-Target Pair
