Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 9726
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476986BDBM476986(Inhibitor 17 of SARS-CoV-2 Mpro | Inhibitor 7 of S...)
Affinity DataIC50: 25nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476992BDBM476992(Inhibitor 12 of SARS-CoV-2 Mpro | US20240092759, C...)
Affinity DataIC50: 27nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476998BDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro | US20240092759, C...)
Affinity DataIC50: 28nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476984BDBM476984(Inhibitor 16 of SARS-CoV-2 Mpro | Inhibitor 6 of S...)
Affinity DataIC50: 37nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476995BDBM476995(Inhibitor 15 of SARS-CoV-2 Mpro)
Affinity DataIC50: 38nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476993BDBM476993(Inhibitor 13 of SARS-CoV-2 Mpro)
Affinity DataIC50: 42nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476999BDBM476999(Inhibitor 19 of SARS-CoV-2 Mpro)
Affinity DataIC50: 44nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484209BDBM484209(Inhibitor 17 of SARS-CoV-2 Mpro)
Affinity DataIC50: 59nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484208BDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataIC50: 61nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484213BDBM484213(Inhibitor 21 of SARS-CoV-2 Mpro)
Affinity DataIC50: 61nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476999BDBM476999(Inhibitor 19 of SARS-CoV-2 Mpro)
Affinity DataEC50:  80nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476988BDBM476988(Inhibitor 9 of SARS-CoV-2 Mpro)
Affinity DataIC50: 83nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476990BDBM476990(Inhibitor 10 of SARS-CoV-2 Mpro | US20240092759, C...)
Affinity DataIC50: 85nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476994BDBM476994(Inhibitor 14 of SARS-CoV-2 Mpro)
Affinity DataIC50: 105nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476981BDBM476981(Inhibitor 4 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataIC50: 120nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476982BDBM476982(Inhibitor 5 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataIC50: 120nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484212BDBM484212(Inhibitor 20 of SARS-CoV-2 Mpro)
Affinity DataIC50: 130nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476991BDBM476991(Inhibitor 11 of SARS-CoV-2 Mpro)
Affinity DataIC50: 131nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476977BDBM476977(Inhibitor 2 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataIC50: 140nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476978BDBM476978(Inhibitor 3 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataIC50: 170nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476999BDBM476999(Inhibitor 19 of SARS-CoV-2 Mpro)
Affinity DataEC50:  175nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476987BDBM476987(Inhibitor 8 of SARS-CoV-2 Mpro)
Affinity DataIC50: 328nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484208BDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  530nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 429505BDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  590nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476988BDBM476988(Inhibitor 9 of SARS-CoV-2 Mpro)
Affinity DataEC50:  730nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 429505BDBM429505(Remdesivir | med.21724, Compound 178 | US202400347...)
Affinity DataEC50:  770nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484209BDBM484209(Inhibitor 17 of SARS-CoV-2 Mpro)
Affinity DataEC50:  820nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476978BDBM476978(Inhibitor 3 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  980nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476998BDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro | US20240092759, C...)
Affinity DataEC50:  1.00E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484213BDBM484213(Inhibitor 21 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.08E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476981BDBM476981(Inhibitor 4 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  1.10E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 484208BDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.20E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476981BDBM476981(Inhibitor 4 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  1.20E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476977BDBM476977(Inhibitor 2 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  1.50E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476977BDBM476977(Inhibitor 2 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  1.51E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476988BDBM476988(Inhibitor 9 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.70E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476978BDBM476978(Inhibitor 3 of SARS-CoV-2 Mpro | US20240092759, Co...)
Affinity DataEC50:  1.76E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476998BDBM476998(Inhibitor 18 of SARS-CoV-2 Mpro | US20240092759, C...)
Affinity DataEC50:  3.20E+3nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 476993BDBM476993(Inhibitor 13 of SARS-CoV-2 Mpro)
Affinity DataEC50: >4.00E+4nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandChemical structure of BindingDB Monomer ID 50184410BDBM50184410(CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...)
Affinity DataIC50: 1.75E+5nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2021
Entry Details Article
PubMed