Found 23 Enz. Inhib. hit(s) with all data for entry = 50014978 
Affinity DataKi: 400nMAssay Description:Antagonist activity at muscarinic M1 receptor (unknown origin) expressed in cells assessed as change in fluorescence measured after 24 hrs by FLIPR a...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PCSK9 translation in human THP-1 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of His-tagged BRD4 (unknown origin) using tetra-acetylated histone H4 peptide as substrate by fluorescent polarization binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of PDE4D3 (unknown origin) assessed as conversion of cAMP to AMP measured after 30 mins by YSi scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PDE5A1 (unknown origin) assessed as conversion of cAMP to AMP measured after 30 mins by YSi scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at dopamine D1 receptor (unknown origin) expressed in cells assessed as change in fluorescence measured after 24 hrs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at histamine H1 receptor (unknown origin) expressed in cells assessed as change in fluorescence measured after 24 hrs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at adrenergic beta2 receptor (unknown origin) expressed in cells measured after 90 mins by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at adrenergic alpha-1A receptor (unknown origin) expressed in cells assessed as change in fluorescence measured after 24 hrs by FLIP...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 1.27E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at cannabinoid receptor 1 (unknown origin) expressed in cells measured after 90 mins by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at serotonin 2B receptor (unknown origin) expressed in cells assessed as change in fluorescence measured after 24 hrs by FLIPR assayMore data for this Ligand-Target Pair
