Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50017619
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50127222BDBM50127222({4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl...)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human PPARdelta expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099491BDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030474BDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603423BDBM50603423(CHEMBL5187974)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603427BDBM50603427(CHEMBL5191280)
Affinity DataEC50:  700nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603423BDBM50603423(CHEMBL5187974)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603422BDBM50603422(CHEMBL5198240)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603427BDBM50603427(CHEMBL5191280)
Affinity DataEC50:  1.78E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603417BDBM50603417(CHEMBL5177968)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240436BDBM50240436(2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecen...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603420BDBM50603420(CHEMBL5182467)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603422BDBM50603422(CHEMBL5198240)
Affinity DataEC50:  3.70E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603421BDBM50603421(CHEMBL5198233)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603424BDBM50603424(CHEMBL5191595)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603419BDBM50603419(CHEMBL5173082)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603418BDBM50603418(CHEMBL4800442)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603421BDBM50603421(CHEMBL5198233)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603417BDBM50603417(CHEMBL5177968)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147581BDBM50147581(n-tetradecanoic acid | tetradecoic acid | myristic...)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240436BDBM50240436(2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecen...)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603419BDBM50603419(CHEMBL5173082)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603426BDBM50603426(CHEMBL5196042)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603420BDBM50603420(CHEMBL5182467)
Affinity DataEC50:  2.90E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239187BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469660BDBM50469660(CHEMBL30915)
Affinity DataEC50:  3.20E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150484BDBM50150484(CHEMBL8659 | oleaic acid | Octadec-9-enoic acid | ...)
Affinity DataEC50:  3.60E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240485BDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603425BDBM50603425(CHEMBL5192854)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603424BDBM50603424(CHEMBL5191595)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603426BDBM50603426(CHEMBL5196042)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239187BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  5.40E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603425BDBM50603425(CHEMBL5192854)
Affinity DataEC50:  6.70E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed