Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50017145
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599974BDBM50599974(CHEMBL5178203)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599972BDBM50599972(CHEMBL5205937)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599972BDBM50599972(CHEMBL5205937)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599970BDBM50599970(CHEMBL5189357)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599971BDBM50599971(CHEMBL5201536)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599973BDBM50599973(CHEMBL5180588)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 374727BDBM374727(US10246466, Example 93 | (7S,13R)-11-fluoro-7,13-d...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599966BDBM50599966(CHEMBL5202081)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599965BDBM50599965(CHEMBL5208156)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599967BDBM50599967(CHEMBL5193888)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599968BDBM50599968(CHEMBL5190535)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599976BDBM50599976(CHEMBL5196111)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599975BDBM50599975(CHEMBL5196924)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599972BDBM50599972(CHEMBL5205937)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599974BDBM50599974(CHEMBL5178203)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599977BDBM50599977(CHEMBL5202709)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599979BDBM50599979(CHEMBL5172208)
Affinity DataIC50: 56nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599978BDBM50599978(CHEMBL5170261)
Affinity DataIC50: 64nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599969BDBM50599969(CHEMBL5193999)
Affinity DataIC50: 74nMAssay Description:Inhibition of wild type TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 136597BDBM136597(US8865698, 14 | US10047097, 14 | US9676783, 14 | U...)
Affinity DataIC50: 140nMAssay Description:Inhibition of TRKA G595R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599974BDBM50599974(CHEMBL5178203)
Affinity DataIC50: 350nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed