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Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50016444
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594996(CHEMBL5205601)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase HCK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM8794(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM8794(1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594997(CHEMBL5188812)
Affinity DataIC50: 1nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594997(CHEMBL5188812)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BTK (unknown origin) transfected in HEK293T cells assessed as reduction in BTK phosphorylation preincubated for 30 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 26nMAssay Description:Inhibition of MNK2 (unknown origin) expressed in HEK293T cells assessed as reduction in eIF4E phosphorylation preincubated for 30 mins followed by AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594995(CHEMBL5196444)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged human full length recombinant BTK expressed in baculovirus infected Sf21 insect cells using YIYGSFK as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 107nMAssay Description:Inhibition of MNK1 (unknown origin) expressed in HEK293T cells assessed as reduction in eIF4E phosphorylation preincubated for 30 mins followed by AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594995(CHEMBL5196444)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His6-tagged human full length recombinant BMX expressed in Sf21 insect cells using TSFYGRH as substrate preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 620nMAssay Description:Inhibition of MNK2 (unknown origin) expressed in HEK293T cells assessed as reduction in eIF4E phosphorylation preincubated for 30 mins followed by AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Nantong University

Curated by ChEMBL
LigandPNGBDBM50594997(CHEMBL5188812)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed