Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50017163
LigandChemical structure of BindingDB Monomer ID 50600115BDBM50600115(CHEMBL5179721 | US20240336588, Compound 51)
Affinity DataIC50: 28nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600113BDBM50600113(CHEMBL5173320 | US20240336588, Compound 40)
Affinity DataIC50: 35nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600122BDBM50600122(CHEMBL5187181 | US20240336588, Compound 47)
Affinity DataIC50: 54nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600121BDBM50600121(CHEMBL5180939 | US20240336588, Compound 46)
Affinity DataIC50: 60nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600125BDBM50600125(CHEMBL5183602 | US20240336588, Compound 55)
Affinity DataIC50: 74nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600116BDBM50600116(CHEMBL5185250 | US20240336588, Compound 41)
Affinity DataIC50: 107nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600114BDBM50600114(CHEMBL5196245 | US20240336588, Compound 38)
Affinity DataIC50: 108nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600123BDBM50600123(CHEMBL5207075 | US20240336588, Compound 48)
Affinity DataIC50: 115nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50236531BDBM50236531((2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3...)
Affinity DataIC50: 121nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600118BDBM50600118(CHEMBL5183972 | US20240336588, Compound 66)
Affinity DataIC50: 145nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50135168BDBM50135168(3,4,5-Trihydroxy-benzoic acid (2R,3S)-5,7-dihydrox...)
Affinity DataIC50: 150nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600120BDBM50600120(CHEMBL5208564 | US20240336588, Compound 45)
Affinity DataIC50: 153nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600112BDBM50600112(CHEMBL5173930 | US20240336588, Compound 42)
Affinity DataIC50: 172nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600127BDBM50600127(CHEMBL5198374)
Affinity DataIC50: 212nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50135169BDBM50135169((2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50070942BDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 232nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600111BDBM50600111(CHEMBL5190113 | US20240336588, Compound 34)
Affinity DataIC50: 236nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600124BDBM50600124(CHEMBL5180222)
Affinity DataIC50: 296nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600126BDBM50600126(CHEMBL5205632 | US20240336588, Compound 39)
Affinity DataIC50: 422nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50296234BDBM50296234((2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 429nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600119BDBM50600119(CHEMBL5191458 | US20240336588, Compound 62)
Affinity DataIC50: 432nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50153015BDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 523nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600117BDBM50600117(CHEMBL5173568 | US20240336588, Compound 63)
Affinity DataIC50: 553nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600128BDBM50600128(CHEMBL5209173 | US20240336588, Compound 53)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600129BDBM50600129(CHEMBL5195624)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50296239BDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed