Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50017850
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605473(CHEMBL5186093)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605464(CHEMBL5188318)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605473(CHEMBL5186093)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human PIM1 expressed in bacterial expression system using histone H1 as substrate measured after 30 mins in presence of ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605464(CHEMBL5188318)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in bacterial expression system using histone H1 as substrate in presence of ATP at measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605464(CHEMBL5188318)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605467(CHEMBL5177344)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605468(CHEMBL5186471)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605467(CHEMBL5177344)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605473(CHEMBL5186093)
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605468(CHEMBL5186471)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCasein kinase I isoform epsilon(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant CK1 epsilon expressed in baculovirus in sf9 insect cells using RRKHAAIGSpAYSITA as substrate in presence of ATP measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605460(CHEMBL5208358)
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 117nMAssay Description:Inhibition of human recombinant PLK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK3(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant JAK3 expressed in baculovirus sf9 insect cells using GGEEEEYFELVKKKK as substrate measured after 30 mins in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605465(CHEMBL5202187)
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 125nMAssay Description:Inhibition of human PLK2 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605468(CHEMBL5186471)
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605466(CHEMBL5194011)
Affinity DataIC50: 148nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50: 148nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605472(CHEMBL5208474)
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant ABL1 expressed in baculovirus sf9 insect cells using EAIYAAPFAKKK as substrate measured after 30 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605459(CHEMBL5198375)
Affinity DataIC50: 169nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605469(CHEMBL5190257)
Affinity DataIC50: 202nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 221nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 294nMAssay Description:Inhibition of human PLK1 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605473(CHEMBL5186093)
Affinity DataIC50: 418nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605470(CHEMBL5179862)
Affinity DataIC50: 432nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605462(CHEMBL5181571)
Affinity DataIC50: 484nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50: 515nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 578nMAssay Description:Inhibition of human DAPK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605467(CHEMBL5177344)
Affinity DataIC50: 594nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605463(CHEMBL5181177)
Affinity DataIC50: 897nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605457(CHEMBL5183366)
Affinity DataIC50: 916nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605471(CHEMBL5181620)
Affinity DataIC50: 917nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605461(CHEMBL5198391)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed