Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with all data for entry = 50002816
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 27-41More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 3 from guinea pig, range 1.9-3.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 120-290More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 27-41More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  3.88E+4nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 1 from guinea pig, range 34-43More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024406(5-(4-Imidazol-1-yl-phenyl)-6-methyl-2-oxo-1,2-dihy...)
Affinity DataIC50:  4.26E+4nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 2 from guinea pig, range 37-49More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 2 from guinea pig, range 120-290More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 2 from guinea pig, range 140-300More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  3.10E+5nMAssay Description:Inhibition of cAMP-phosphodiesterase PDE 1 from guinea pig, range 190-430More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibition of cGMP phosphodiesterase PDE 1 from guinea pig, range 170-510More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed