Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50015925
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 12nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590561(CHEMBL5184562)
Affinity DataIC50: 23nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590560(CHEMBL5201017)
Affinity DataIC50: 23nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataIC50: 37nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590562(CHEMBL5200916)
Affinity DataIC50: 93nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590563(CHEMBL5190868)
Affinity DataIC50: 136nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590561(CHEMBL5184562)
Affinity DataIC50: 195nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590560(CHEMBL5201017)
Affinity DataIC50: 407nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 463nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590563(CHEMBL5190868)
Affinity DataIC50: 866nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50590562(CHEMBL5200916)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate and measured by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed