Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50016996
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 350nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 370nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598953(CHEMBL39183)
Affinity DataIC50: 810nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598952(CHEMBL5176579)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598947(CHEMBL274452)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50013811(9H-pyrido[3,4-b]indole | Norharman | CHEMBL275224 ...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598951(CHEMBL5186390)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598947(CHEMBL274452)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598939(CHEMBL5172850)
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598950(CHEMBL5196062)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50013786(cid_5281404 | Harmane | 1-Methyl-beta-carboline | ...)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50205688(CHEMBL3975325)
Affinity DataIC50: 7.24E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598937(CHEMBL5187479)
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598942(CHEMBL5207121)
Affinity DataIC50: 8.28E+3nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598937(CHEMBL5187479)
Affinity DataIC50: 8.29E+3nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598943(CHEMBL2030639)
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598946(CHEMBL38596)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598949(CHEMBL5195626)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598945(CHEMBL5194494)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598936(CHEMBL5180636)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598948(CHEMBL5188549)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598944(CHEMBL5184595)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598938(CHEMBL5195156)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598948(CHEMBL5188549)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598939(CHEMBL5172850)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598941(CHEMBL5207671)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598940(CHEMBL5185419)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598944(CHEMBL5184595)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598946(CHEMBL38596)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598945(CHEMBL5194494)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50598936(CHEMBL5180636)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 1 hr by absorbance b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed