Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50018683
TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611370(CHEMBL5283992)
Affinity DataIC50: 680nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611371(CHEMBL5284393)
Affinity DataIC50: 860nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611375(CHEMBL5272043)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611376(CHEMBL5275186)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLethal factor(Bacillus anthracis)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50485657(CHEMBL2146996)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611376(CHEMBL5275186)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611375(CHEMBL5272043)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLethal factor(Bacillus anthracis)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50278743(AM-2S | N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of anthrax lethal factorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611373(CHEMBL5265823)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611374(CHEMBL5284891)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611372(CHEMBL5290572)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50556582(CHEMBL4797501)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50366038(CHEMBL1356238)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MMP-3 (unknown origin) by Colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611375(CHEMBL5272043)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611376(CHEMBL5275186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611375(CHEMBL5272043)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611376(CHEMBL5275186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611375(CHEMBL5272043)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50611376(CHEMBL5275186)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50366038(CHEMBL1356238)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of MMP-3 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50158402(CHEMBL3781198)
Affinity DataIC50: 4.88E+4nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50086229(CHEMBL326815)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed