Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50019281
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617574(CHEMBL5410025)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617570(CHEMBL5424370)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617583(CHEMBL5428487)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617582(CHEMBL5419335)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617585(CHEMBL5428372)
Affinity DataKi:  129nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617584(CHEMBL5406967)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617581(CHEMBL5413550)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617575(CHEMBL5418589)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617577(CHEMBL5409408)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617573(CHEMBL5430360)
Affinity DataKi:  456nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617580(CHEMBL5422404)
Affinity DataKi:  465nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617571(CHEMBL5409471)
Affinity DataKi:  485nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617570(CHEMBL5424370)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH-477 induced cAMP production incubated for 30 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617582(CHEMBL5419335)
Affinity DataKi:  754nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 60 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617572(CHEMBL5421210)
Affinity DataKi:  923nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617576(CHEMBL5415690)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617579(CHEMBL5422557)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617583(CHEMBL5428487)
Affinity DataEC50:  5.25E+3nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH-477 induced cAMP production incubated for 30 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617581(CHEMBL5413550)
Affinity DataEC50:  5.60E+3nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH-477 induced cAMP production incubated for 30 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617578(CHEMBL5437097)
Affinity DataKi:  6.50E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50617577(CHEMBL5409408)
Affinity DataEC50:  1.04E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH-477 induced cAMP production incubated for 30 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of The Studies of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50180036(CHEMBL371214 | (6aR,10aR)-3-(1,1-dimethylbutyl)-6a...)
Affinity DataEC50:  1.69E+5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of NKH-477 induced cAMP production incubated for 30 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed