Compile Data Set for Download or QSAR
Report error Found 138 Enz. Inhib. hit(s) with all data for entry = 50019348
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20608BDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataEC50:  0.0990nMAssay Description:Antagonist activity against ERalpha in estradiol stimulated HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataEC50:  0.418nMAssay Description:Antagonist activity against ERalpha in estradiol stimulated HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238741BDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataEC50:  0.665nMAssay Description:Antagonist activity against ERbeta in estradiol stimulated HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618348BDBM50618348(CHEMBL5433442)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618352BDBM50618352(CHEMBL5412790)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13061BDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618359BDBM50618359(CHEMBL5405944)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618360BDBM50618360(CHEMBL5421409)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618353BDBM50618353(CHEMBL5411799)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618383BDBM50618383(CHEMBL5404063)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity against ERbeta in HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618361BDBM50618361(CHEMBL5408038)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618354BDBM50618354(CHEMBL5400803)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618356BDBM50618356(CHEMBL5417452)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618380BDBM50618380(CHEMBL5423258)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618345BDBM50618345(CHEMBL5418690)
Affinity DataKi:  23nMAssay Description:Binding affinity to ERbeta (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618372BDBM50618372(CHEMBL5433532)
Affinity DataKi:  25nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618364BDBM50618364(CHEMBL5400203)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618363BDBM50618363(CHEMBL5426947)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618386BDBM50618386(CHEMBL5394879)
Affinity DataKi:  35nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618388BDBM50618388(CHEMBL5398866)
Affinity DataKi:  36nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618355BDBM50618355(CHEMBL5420394)
Affinity DataKi:  38nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618383BDBM50618383(CHEMBL5404063)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618383BDBM50618383(CHEMBL5404063)
Affinity DataEC50:  39.6nMAssay Description:Antagonist activity against ERalpha in estradiol stimulated HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618352BDBM50618352(CHEMBL5412790)
Affinity DataEC50:  53.5nMAssay Description:Antagonist activity against ERalpha in estradiol stimulated HEK293T cells measuring luciferase activity after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618357BDBM50618357(CHEMBL5422315)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618376BDBM50618376(CHEMBL5419649)
Affinity DataKi:  55nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618360BDBM50618360(CHEMBL5421409)
Affinity DataKi:  55nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618348BDBM50618348(CHEMBL5433442)
Affinity DataKi:  55nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618380BDBM50618380(CHEMBL5423258)
Affinity DataKi:  61nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618353BDBM50618353(CHEMBL5411799)
Affinity DataKi:  68nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618368BDBM50618368(CHEMBL5426251)
Affinity DataKi:  70nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618361BDBM50618361(CHEMBL5408038)
Affinity DataKi:  72nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618354BDBM50618354(CHEMBL5400803)
Affinity DataKi:  72nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618366BDBM50618366(CHEMBL5404699)
Affinity DataKi:  73nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618383BDBM50618383(CHEMBL5404063)
Affinity DataKi:  75nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50564412BDBM50564412(CHEMBL4800654)
Affinity DataKi:  76nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618343BDBM50618343(CHEMBL5394546)
Affinity DataKi:  77nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618377BDBM50618377(CHEMBL5394007)
Affinity DataKi:  78nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618362BDBM50618362(CHEMBL5427513)
Affinity DataKi:  84nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618352BDBM50618352(CHEMBL5412790)
Affinity DataKi:  84nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618377BDBM50618377(CHEMBL5394007)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618387BDBM50618387(CHEMBL5432102)
Affinity DataKi:  90nMAssay Description:Binding affinity to ERbeta (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618381BDBM50618381(CHEMBL5423781)
Affinity DataKi:  92nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618350BDBM50618350(CHEMBL5403786)
Affinity DataKi:  93nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618349BDBM50618349(CHEMBL5436925)
Affinity DataKi:  100nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618369BDBM50618369(CHEMBL5435743)
Affinity DataKi:  100nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618351BDBM50618351(CHEMBL5410004)
Affinity DataKi:  100nMAssay Description:Binding affinity to ERalpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618382BDBM50618382(CHEMBL5428681)
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618347BDBM50618347(CHEMBL5426175)
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAromatase(Human)
Zhongnan Hospital of Wuhan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618349BDBM50618349(CHEMBL5436925)
Affinity DataIC50: 103nMAssay Description:Inhibition of human recombinant aromatase using ARO as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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