Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50020412
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629720BDBM50629720(CHEMBL5396836)
Affinity DataIC50: 10nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629719BDBM50629719(CHEMBL5409427)
Affinity DataIC50: 10nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629728BDBM50629728(CHEMBL5399843)
Affinity DataIC50: 30nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629719BDBM50629719(CHEMBL5409427)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629716BDBM50629716(CHEMBL5437146)
Affinity DataIC50: 70nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629714BDBM50629714(CHEMBL5400914)
Affinity DataIC50: 90nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate assessed as reduction in PGF2alpha level preincubated for 5 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629720BDBM50629720(CHEMBL5396836)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629715BDBM50629715(CHEMBL5424814)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629725BDBM50629725(CHEMBL5403984)
Affinity DataIC50: 140nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629716BDBM50629716(CHEMBL5437146)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629731BDBM50629731(CHEMBL5418745)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 500nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629722BDBM50629722(CHEMBL5401155)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629718BDBM50629718(CHEMBL5433854)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629717BDBM50629717(CHEMBL5404402)
Affinity DataIC50: 660nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629732BDBM50629732(CHEMBL5400672)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13066BDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 820nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13066BDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629724BDBM50629724(CHEMBL5434060)
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629730BDBM50629730(CHEMBL5399127)
Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629725BDBM50629725(CHEMBL5403984)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32020BDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of 15-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629729BDBM50629729(CHEMBL5403487)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629723BDBM50629723(CHEMBL5425523)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629726BDBM50629726(CHEMBL5406863)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13066BDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13066BDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629728BDBM50629728(CHEMBL5399843)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629717BDBM50629717(CHEMBL5404402)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629724BDBM50629724(CHEMBL5434060)
Affinity DataIC50: 7.03E+3nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629727BDBM50629727(CHEMBL5423229)
Affinity DataIC50: 7.68E+3nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 8.77E+3nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629731BDBM50629731(CHEMBL5418745)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629729BDBM50629729(CHEMBL5403487)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629722BDBM50629722(CHEMBL5401155)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629715BDBM50629715(CHEMBL5424814)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629721BDBM50629721(CHEMBL5411339)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629718BDBM50629718(CHEMBL5433854)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629730BDBM50629730(CHEMBL5399127)
Affinity DataIC50: 3.71E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629732BDBM50629732(CHEMBL5400672)
Affinity DataIC50: 9.26E+4nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629723BDBM50629723(CHEMBL5425523)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629721BDBM50629721(CHEMBL5411339)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629726BDBM50629726(CHEMBL5406863)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629727BDBM50629727(CHEMBL5423229)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed