Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50022277
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650167(CHEMBL5631165)
Affinity DataKi:  0.00500nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM554453(US11332492, Example 2)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human CD73 expressed in A-375 cells incubated for 15 mins by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650169(CHEMBL5624492)
Affinity DataKi:  0.318nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650168(CHEMBL5630200)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50368125(ADP | ADENOSINE DIPHOSPHATE)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CD73 expressed in A-375 cells incubated for 15 mins by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650173(CHEMBL5630919)
Affinity DataKi:  10nMAssay Description:Binding affinity to human recombinant CD73 expressed in Sf9 cells assessed as inhibition constant by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM554453(US11332492, Example 2)
Affinity DataIC50: 50nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant CD73 expressed in CHO cells incubated for 1 hr by malachite green based spectrophotometer assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50368125(ADP | ADENOSINE DIPHOSPHATE)
Affinity DataKi:  88nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetB-cell antigen receptor complex-associated protein beta chain(Homo sapiens)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650171(CHEMBL5630968)
Affinity DataKi:  97nMAssay Description:Binding affinity to human recombinant CD79 expressed in Sf9 cells assessed as inhibition constant by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50561206(CHEMBL4764985)
Affinity DataIC50: 250nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant CD73 expressed in CHO cells incubated for 1 hr by malachite green based spectrophotometer assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650171(CHEMBL5630968)
Affinity DataKi:  451nMAssay Description:Binding affinity to human recombinant CD73 expressed in Sf9 cells assessed as inhibition constant by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50640561(CHEMBL5574428)
Affinity DataIC50: 470nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50640559(CHEMBL5572739)
Affinity DataIC50: 560nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50640560(CHEMBL5573566)
Affinity DataIC50: 740nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650170(CHEMBL5630182)
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant CD73 (27 to 549 residues) expressed in Sf9 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650170(CHEMBL5630182)
Affinity DataIC50: 860nMAssay Description:Inhibition of C-terminal 6His-tagged human recombinant CD73 expressed in CHO cells incubated for 1 hr by malachite green based spectrophotometer assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50599943(CHEMBL5177276)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50626493(CHEMBL5436167)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human recombinant CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataKi:  7.80E+3nMAssay Description:Binding affinity to CD73 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650172(CHEMBL5630419)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity to human recombinant CD73 expressed in Sf9 cells assessed as inhibition constant by malachite green based spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50650172(CHEMBL5630419)
Affinity DataKi:  1.63E+4nMAssay Description:Binding affinity to human NPP1 expressed in Sf9 cells assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed