Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50022293
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM50567694(CHEMBL4858994)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human HDAC6 expressed in baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length human recombinant HDAC6 (379 to 382 residues) expressed in baculovirus infected Sf9 insect cells using (RHKK(Ac)AMC) as a f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal FLAG-tagged full length human recombinant HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of C-terminal FLAG-tagged human recombinant HDAC1 expressed in baculovirus by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM50650416(CHEMBL5629859)
Affinity DataIC50: 15nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50365501(CHEMBL1957458)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50538730(CHEMBL4635503)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50567694(CHEMBL4858994)
Affinity DataIC50: 254nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by compound addition and measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM50649028(CHEMBL5618867)
Affinity DataIC50: 380nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50649028(CHEMBL5618867)
Affinity DataIC50: 510nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 559nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human recombinant HDAC8 expressed in baculovirusMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM50650415(CHEMBL5630869)
Affinity DataIC50: 559nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human recombinant HDAC2 expressed in Sf9 cells by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM50365501(CHEMBL1957458)
Affinity DataIC50: 670nMAssay Description:Inhibition of HDAC2 (unknown origin) using Fluor de lys as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 870nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM50649028(CHEMBL5618867)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of full length human recombinant HDAC8 (379 to 382 residues) expressed in baculovirus infected Sf9 insect cells using (RHK(Ac)K(Ac)AMC) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 (379 to 382 residues) expressed in baculovirus infected Sf9 insect cells using (RHKK(Ac)AMC) as a f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed