Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50020449
TargetBeta-glucuronidase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629976(CHEMBL5409470)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human GUSbeta using 4-MUG as substrate pre-incubated for 10 mins followed by substrate addition and measured after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629971(CHEMBL5404984)
Affinity DataIC50: 442nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629976(CHEMBL5409470)
Affinity DataIC50: 467nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629975(CHEMBL5417506)
Affinity DataIC50: 586nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629974(CHEMBL5402679)
Affinity DataIC50: 748nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629971(CHEMBL5404984)
Affinity DataIC50: 839nMAssay Description:Inhibition of recombinant human GUSbeta using 4-MUG as substrate pre-incubated for 10 mins followed by substrate addition and measured after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629977(CHEMBL5434518)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629973(CHEMBL5402077)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629980(CHEMBL5395568)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629979(CHEMBL5431219)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629978(CHEMBL5433394)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629972(CHEMBL5432983)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50405568(CHEMBL5273557)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629981(CHEMBL5420418)
Affinity DataIC50: 9.95E+3nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed