Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50022422
LigandPNGBDBM50617261(CHEMBL5414287)
Affinity DataKd:  110nMAssay Description:Binding affinity to GRP78 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50617261(CHEMBL5414287)
Affinity DataIC50: 590nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652104(CHEMBL5639838)
Affinity DataKd:  625nMAssay Description:Binding affinity to human recombinant full length HSPA8 (42 to 401 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652104(CHEMBL5639838)
Affinity DataKd:  679nMAssay Description:Binding affinity to GRP78 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM77529(N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxyquinoli...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of GRP78 (unknown origin) by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652104(CHEMBL5639838)
Affinity DataKd:  1.63E+3nMAssay Description:Binding affinity to HSPA1A (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM77529(N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxyquinoli...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetAromatase(Human)TBA
LigandPNGBDBM50042944(cid_638278 | (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hyd...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of aromatase (unknown origin) assessed as inhbition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50617258(CHEMBL5424525)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50617257(CHEMBL5308000)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM31712(SMR000058356 | MLS000028433 | cid_3598 | HEXACHLOR...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of GRP78 (unknown origin) by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50042944(cid_638278 | (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hyd...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of SIRT1 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50042944(cid_638278 | (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hyd...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of FLT3 (unknown origin) using 33P-ATP as substrate incubated for 120 mins by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50617256(CHEMBL5415251)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to GRP78 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652105(CHEMBL5415522)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652107(CHEMBL5395687)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50652106(CHEMBL5422201)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged human recombinant GRP78 expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed