Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50021501
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50032821(CHEMBL3355178)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622479(CHEMBL5404581)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622460(CHEMBL5413819)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622457(CHEMBL5419652)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094465(CHEMBL3590106 | US10525036, Example BVD-523 | US10...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622457(CHEMBL5419652)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622479(CHEMBL5404581)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM610464(US10774086, Example 15 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641321(CHEMBL5574740)
Affinity DataIC50: 1nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM35657(pyrimidylpyrrole, 11e)
Affinity DataKi: <2nMAssay Description:Binding affinity to human recombinant ERK2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641322(CHEMBL5564918)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of JNK2 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641319(CHEMBL5575110)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641316(CHEMBL5569575)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50613394(CHEMBL5278465)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50415046(CHEMBL583658)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human CDK5/p25 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP by radiometric scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601414(CHEMBL5173945)
Affinity DataIC50: 9nMAssay Description:Inhibition of GSK3alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601414(CHEMBL5173945)
Affinity DataIC50: 9nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641320(CHEMBL5569189)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622457(CHEMBL5419652)
Affinity DataIC50: 10nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601414(CHEMBL5173945)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged human recombinant GSK3beta expressed in Sf9 cells using biotinylated peptide bio-LC-S-R-H-S-S-P-H-Q-pS-E-D-E-E-E-OH as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622479(CHEMBL5404581)
Affinity DataIC50: 12nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641322(CHEMBL5564918)
Affinity DataIC50: 21nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM92522(Aminopyrazole inhibitor, 3451)
Affinity DataIC50: 25nMAssay Description:Inhibition of JNK3 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ATF2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641318(CHEMBL5574538)
Affinity DataIC50: 28nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50559422(CHEMBL4778645)
Affinity DataIC50: 33nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641314(CHEMBL5574221)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSK3beta (unknown origin) assessed as fluorescence intensity by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50559430(CHEMBL4753641)
Affinity DataIC50: 35nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641318(CHEMBL5574538)
Affinity DataKd:  46nMAssay Description:Binding affinity to JNK3 (unknown origin) assessed as dissociation constant by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50621792(CHEMBL5437462)
Affinity DataKd:  46nMAssay Description:Binding affinity to JNK3 (unknown origin) assessed as dissociation constant by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50622460(CHEMBL5413819)
Affinity DataIC50: 49nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50559420(CHEMBL4784092)
Affinity DataIC50: 53nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM610464(US10774086, Example 15 | N-(4-(2-Methylmorpholino)...)
Affinity DataIC50: 58nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641316(CHEMBL5569575)
Affinity DataIC50: 74nMAssay Description:Inhibition of JNK3 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ATF2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50633330(CHEMBL5432203)
Affinity DataIC50: 78nMAssay Description:Inhibition of JNK3 (unknown origin) by kinase profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50515259(CHEMBL4470981)
Affinity DataIC50: 100nMAssay Description:Inhibition of JNK3 (unknown origin) by kinase profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641322(CHEMBL5564918)
Affinity DataIC50: 100nMAssay Description:Inhibition of JNK1 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50415046(CHEMBL583658)
Affinity DataIC50: 108nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641321(CHEMBL5574740)
Affinity DataIC50: 143nMAssay Description:Inhibition of JNK2 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641313(CHEMBL5570879)
Affinity DataIC50: 149nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641313(CHEMBL5570879)
Affinity DataIC50: 178nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in Sf9 insect cells using histone H1 and ATP as substrate in presence of as substrate by radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50613394(CHEMBL5278465)
Affinity DataIC50: 200nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 206nMAssay Description:Inhibition of JNK2 (unknown origin) by discoverX kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50032821(CHEMBL3355178)
Affinity DataIC50: 210nMAssay Description:Inhibition of JNK3 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ATF2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641319(CHEMBL5575110)
Affinity DataIC50: 225nMAssay Description:Inhibition of JNK2 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641321(CHEMBL5574740)
Affinity DataIC50: 298nMAssay Description:Inhibition of JNK1 (unknown origin) by HotSpot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50032750(CHEMBL3355181)
Affinity DataIC50: 311nMAssay Description:Inhibition of JNK3 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ATF2 as substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-phenylH-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyraz...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50641316(CHEMBL5569575)
Affinity DataIC50: 387nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM92522(Aminopyrazole inhibitor, 3451)
Affinity DataIC50: 400nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601414(CHEMBL5173945)
Affinity DataIC50: 466nMAssay Description:Inhibition of tau phosphorylation (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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