Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50022454
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant GST tagged-EGFR using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant N-terminal GST tagged-c-KIT (544 to end residues) expressed in baculovirus infected Sf9 cells using Poly (Glu,Tyr) 4:...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant GST tagged-ROS1 using IRF-1Rtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant GST tagged-EGFR using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human recombinant GST tagged-RET using IRF-1Rtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Inhibition of human recombinant N-terminal GST tagged-c-KIT (544 to end residues) expressed in baculovirus infected Sf9 cells using Poly (Glu,Tyr) 4:...More data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 212nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 217nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 235nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 289nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 334nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 354nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of human CDK2 by ELISA analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 462nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Affinity DataIC50: 537nMAssay Description:Inhibition of human recombinant GST tagged-RET using IRF-1Rtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair




3D Structure (crystal)




















