Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50022379
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) preincubated for 60 mins in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) preincubated for 60 mins in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) preincubated for 60 mins in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataKd: 87nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataKd: 440nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataKd: 440nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataIC50: 449nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataIC50: 584nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 678nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataKd: 680nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: 710nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataKd: 880nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: 900nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) preincubated for 60 mins in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) preincubated for 60 mins in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of AURKB/INCENP (unknown origin) in the presence of ATP at Km concentrationMore data for this Ligand-Target Pair
Affinity DataKd: 4.80E+3nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataKd: 9.80E+3nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of AURKB (unknown origin) by nanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataKd: 3.00E+4nMAssay Description:Binding affinity to human partial length EGFR (R669 to V1011 residues) L858R mutant expressed in bacterial expression system assessed as dissociation...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to human partial length AURKB (D25 to A303 residues) expressed in mammalian system assessed as dissociation constant by DiscoverX ki...More data for this Ligand-Target Pair
Affinity DataKd: 3.00E+4nMAssay Description:Binding affinity to wild type human EGFR partial length (R669 to V1011 residues) expressed in bacterial expression system assessed as dissociation co...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation (unknown origin) preincubated for 60 mins in the presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 4.56E+4nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 4.76E+4nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of EGFR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell survivalMore data for this Ligand-Target Pair
