Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50021699
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50373059(CHEMBL429317)
Affinity DataEC50:  700nMAssay Description:Type-1 positive allosteric modulation of wild type human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50573069(CHEMBL4857008)
Affinity DataEC50:  1.04E+3nMAssay Description:Type-II positive allosteric modulation of alpha7 nAChR in human IMR-32 cells assessed as increase in choline chloride-induced Ca2+ flux preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643644(CHEMBL5569159)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643643(CHEMBL5591884)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50374402(PNU-120596 | CHEMBL257591)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of rat alpha7 nAChR expressed in xenopus laevis oocytes assessed as potentiation of acetylcholine induced channel acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643641(CHEMBL5568756)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50374404(JNJ-1930942 | CHEMBL270479)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in rat GH4-C1 cells assessed as potentiation of choline-induced Ca2+ level preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643654(CHEMBL5562542)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643653(CHEMBL5571266)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643651(CHEMBL5565974)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50374402(PNU-120596 | CHEMBL257591)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643632(CHEMBL5563649)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643637(CHEMBL5575576)
Affinity DataEC50:  3.00E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50374401(CHEMBL407217)
Affinity DataEC50:  3.40E+3nMAssay Description:Type-1 positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643646(CHEMBL5573097)
Affinity DataEC50:  3.80E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643635(CHEMBL5568872)
Affinity DataEC50:  4.00E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643636(CHEMBL5591732)
Affinity DataEC50:  4.10E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643647(CHEMBL5583588)
Affinity DataEC50:  4.10E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643650(CHEMBL5571712)
Affinity DataEC50:  4.50E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643631(CHEMBL5574142)
Affinity DataEC50:  4.80E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643633(CHEMBL5573180)
Affinity DataEC50:  5.40E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643645(CHEMBL5575611)
Affinity DataEC50:  6.50E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643648(CHEMBL5571361)
Affinity DataEC50:  6.70E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643649(CHEMBL5567203)
Affinity DataEC50:  7.00E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643652(CHEMBL5572962)
Affinity DataEC50:  8.30E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50573068(CHEMBL4864054)
Affinity DataEC50:  8.30E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as potentiation of acetylcholine induced ionic curr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643642(CHEMBL5568670)
Affinity DataEC50:  9.20E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643640(CHEMBL5565697)
Affinity DataEC50:  9.70E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643634(CHEMBL5571385)
Affinity DataEC50:  1.03E+4nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643639(CHEMBL5573508)
Affinity DataEC50:  1.55E+4nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643638(CHEMBL5570115)
Affinity DataEC50:  4.70E+4nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as increase in acetylcholine induced channel curren...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50643644(CHEMBL5569159)
Affinity DataEC50:  6.12E+4nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in xenopus laevis oocytes assessed as potentiation of acetylcholine induced channel cu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed